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Wegovy tablets (oral semaglutide) and vomiting: causes, tips and when to get help

Vomiting on Wegovy tablets (oral semaglutide): why it happens, self-care measures and the warning signs that need medical help.

About vomiting on Wegovy tablets (oral semaglutide)

Being sick can occur alongside nausea, most often around the start of treatment or a dose increase. Repeated vomiting can lead to dehydration, which can affect the kidneys.

Vomiting is listed among the commonly reported side effects of Wegovy tablets (oral semaglutide) in our reference data.

Things that may help

  • Take small, frequent sips of water or an oral rehydration solution
  • Return to small, plain meals once you can keep fluids down
  • Avoid large or high-fat meals

A pharmacist can advise on suitable over-the-counter options.

Speak to your prescriber if

  • you have vomited more than once in a day, or vomiting keeps coming back
  • you think vomiting may be affecting other medicines you take, including oral contraception

Report suspected side effects through the MHRA Yellow Card scheme. Reports help the MHRA monitor the safety of medicines.

Frequently asked questions

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