Wegovy tablets (oral semaglutide) and indigestion and reflux: causes, tips and when to get help
Indigestion and reflux on Wegovy tablets (oral semaglutide): why it happens, self-care measures and the warning signs that need medical help.
Get urgent medical help if:
- you have chest pain, especially if it spreads to your arm, jaw or back, or comes with breathlessness (call 999)
- you vomit blood or have black, tarry stools
Call 999 or go to A&E in an emergency. For urgent advice, call NHS 111.
About indigestion and reflux on Wegovy tablets (oral semaglutide)
Indigestion, heartburn and acid reflux are reported with GLP-1 medicines, which keep food in the stomach for longer.
Indigestion and reflux is listed among the commonly reported side effects of Wegovy tablets (oral semaglutide) in our reference data.
Things that may help
- Eat smaller meals and avoid eating late in the evening
- Keep your head and shoulders raised in bed if reflux is worse at night
- Notice and limit foods that trigger symptoms for you
- Ask a pharmacist whether an antacid is suitable alongside your other medicines
A pharmacist can advise on suitable over-the-counter options.
Speak to your prescriber if
- symptoms persist despite self-care
- you have difficulty or pain when swallowing
Report suspected side effects through the MHRA Yellow Card scheme. Reports help the MHRA monitor the safety of medicines.