Every Weight Loss Medication Available in the UK
An overview of UK weight loss medicines: orlistat, liraglutide, semaglutide, tirzepatide, the new GLP-1 tablets and others, with licence and NICE status.
13 min read
Guides
Evidence-based guides written from SmPCs, NICE guidance and peer-reviewed trials. Every guide is clinically reviewed before it is published.
Medications
Medications Medications Foundayo (Orforglipron): The Small-Molecule GLP-1 Tablet Explained
Foundayo (orforglipron) explained: how the small-molecule GLP-1 tablet works, UK licensing, doses, ATTAIN trial results, side effects and key interactions.
13 min read
Medications How Mounjaro Works: GIP and GLP-1 Explained
A plain-English explanation of how Mounjaro (tirzepatide) works on GIP and GLP-1 receptors to reduce appetite, slow digestion and improve blood sugar.
12 min read
Medications How Wegovy Works: Semaglutide and Appetite Explained
How Wegovy (semaglutide) works: the GLP-1 hormone, its effects on the brain, stomach and pancreas, why it reduces appetite and what happens when you stop.
12 min read
Medications Mounjaro in the UK: The Complete Guide to Tirzepatide for Weight Loss
An evidence-based guide to Mounjaro (tirzepatide) in the UK: how it works, who it is licensed for, trial results, side effects, NHS and private access.
13 min read
Medications Oral GLP-1 Medications in the UK: The Complete Guide
Wegovy tablets, Foundayo and Rybelsus explained: how oral GLP-1 medicines work, UK licensing, trial results, how to take them and who they may suit.
13 min read
Costs and pricing
Costs and pricing How Weight Loss Injection Pricing Works in the UK
Why Mounjaro, Wegovy and Saxenda cost different amounts from different UK providers, what is included in the price and how to compare fairly.
12 min read
Costs and pricing Mounjaro Prices in the UK: What Affects the Cost
What affects the cost of Mounjaro in the UK: dose strength, the September 2025 list-price rise, provider fees, NHS charges and how to compare like for like.
12 min read
Costs and pricing Private vs NHS Weight Loss Treatment
How NHS and private weight loss injections compare in the UK: eligibility, waiting times, which medicines are offered, support, regulation and cost.
13 min read
Costs and pricing The 2025 Mounjaro Price Rise: What Happened and What It Means
Why Eli Lilly raised the UK list price of Mounjaro in September 2025, how it affected private patients and the NHS, and what to consider now.
12 min read
Costs and pricing The Hidden Costs of Private Weight Loss Treatment
Costs of private weight loss injections beyond the pen price, from consultations and supplies to side-effect remedies, clothing and long-term treatment.
12 min read
Costs and pricing The Long-Term Cost of GLP-1 Treatment
Why the total cost of GLP-1 weight loss treatment depends on how long you take it, what trials show about stopping, and how to plan for the long term.
12 min read
Side effects
Side effects Burping, Reflux and Indigestion on GLP-1 Medication
Why Mounjaro and Wegovy can cause sulphur burps, heartburn, reflux and indigestion, practical ways to ease symptoms and the warning signs that need a doctor.
12 min read
Side effects Constipation on GLP-1 Medication
Why Mounjaro, Wegovy and other GLP-1s cause constipation, how common it is, and steps on fibre, fluids, activity and laxatives, and warning signs.
12 min read
Side effects Diarrhoea on GLP-1 Medication
Why Mounjaro, Wegovy and other GLP-1 medicines can cause diarrhoea, how common it is, self-care steps, dehydration risks and when to get medical help.
13 min read
Side effects Facial Changes and Loose Skin After GLP-1 Weight Loss
What 'Ozempic face' really means, why loose skin happens after major weight loss on GLP-1 medicines, what may help and how to approach cosmetic options safely.
12 min read
Side effects GLP-1 Medication and Gallbladder Problems
How Mounjaro, Wegovy and other GLP-1 medicines relate to gallstones and cholecystitis, what the trial data show, symptoms to watch for and when to get help.
12 min read
Side effects GLP-1 Medication and Pancreatitis: Understanding the Risk
What the MHRA's 2026 strengthened warning means for Mounjaro and Wegovy users: how rare pancreatitis is, symptoms, risk factors and when to seek help.
14 min read
Doses and dosing
Doses and dosing How to Use the Mounjaro KwikPen
A step-by-step guide to the Mounjaro KwikPen: checking the pen, attaching a needle, priming, injecting, choosing sites, storage and safe disposal.
11 min read
Doses and dosing How to Use the Wegovy FlexTouch Pen
Step-by-step guide to the Wegovy FlexTouch pen: flow checks, injection sites, holding time, storage, missed doses and the 7.2mg dose, from the UK leaflet.
12 min read
Doses and dosing Missed a Mounjaro Dose? What the Guidance Says
What to do if you miss a Mounjaro injection: the four-day rule from the UK product information, changing your injection day, longer gaps and when to get advice.
12 min read
Doses and dosing Mounjaro Doses Explained: The 2.5mg to 15mg Titration Schedule
How Mounjaro dosing works in the UK: the 2.5mg starting dose, four-weekly increases, maintenance doses, the 15mg maximum and how prescribers decide.
12 min read
Doses and dosing Wegovy Doses Explained: The 0.25mg to 2.4mg Titration Schedule
The Wegovy dose schedule explained: why it starts at 0.25mg, how it rises to 2.4mg, the 7.2mg option, missed doses and changing your injection day.
12 min read
Eligibility
Eligibility BMI Explained: How It Decides Treatment Eligibility
What BMI is, how it is calculated, its limitations, and how BMI thresholds decide eligibility for weight loss injections privately and on the NHS.
12 min read
Eligibility Lower BMI Thresholds for South Asian, Chinese, Black African and Caribbean People
Why NICE recommends lower BMI thresholds for some ethnic groups, the evidence behind them, and how they affect eligibility for weight loss injections in the UK.
12 min read
Eligibility Mounjaro on the NHS: NICE Guidance, Eligibility and the Rollout
How NHS access to Mounjaro works: NICE TA1026, the phased rollout in England, who is eligible now, ethnicity-adjusted BMI thresholds and how to ask your GP.
12 min read
Eligibility The Online Weight Loss Consultation: What Prescribers Ask and Why
What happens in a UK online weight loss consultation: the questions prescribers ask, the checks they make and why each one matters for your safety.
12 min read
Eligibility Wegovy on the NHS: NICE TA875, Specialist Services and Access
Who can get Wegovy on the NHS under NICE TA875 and TA1152, how specialist weight management services work, the two-year limit and what affects access.
13 min read
Eligibility Who Can Get Weight Loss Injections in the UK?
Who is eligible for weight loss injections such as Mounjaro and Wegovy in the UK, privately and on the NHS, and who may not be suitable.
12 min read
Comparisons
Comparisons Every UK Weight Loss Injection Compared
An evidence-based comparison of Mounjaro, Wegovy and Saxenda in the UK: how they work, trial results, dosing, side effects and NHS access.
14 min read
Comparisons GLP-1 Medication vs Bariatric Surgery
How weight loss injections such as Mounjaro and Wegovy compare with bariatric surgery in the UK: results, risks, eligibility and long-term commitment.
13 min read
Comparisons Mounjaro vs Oral GLP-1 Tablets
Mounjaro injections compared with GLP-1 tablets (Wegovy tablets and Foundayo): trial results, side effects, daily routine, switching and UK access.
13 min read
Comparisons Mounjaro vs Wegovy: An Evidence-Based Comparison
Mounjaro (tirzepatide) and Wegovy (semaglutide) compared: how they work, SURMOUNT-5 head-to-head results, side effects, dosing, NHS access and safety.
13 min read
Comparisons Orlistat vs GLP-1 Medications: How They Compare
Orlistat and GLP-1 medicines such as Mounjaro and Wegovy work very differently. Compare how they work, trial results, side effects and UK access.
13 min read
Comparisons Ozempic vs Wegovy: Same Molecule, Different Licence
Ozempic and Wegovy both contain semaglutide. How their UK licences, doses, pens, evidence and NHS routes differ, and why they are not interchangeable.
11 min read
Results and evidence
Results and evidence Measuring Progress Beyond the Scales
How to track progress on GLP-1 treatment beyond body weight: waist-to-height ratio, blood pressure, blood tests, fitness, strength, sleep and wellbeing.
12 min read
Results and evidence Mounjaro Results: What the Trials Show Over Time
What the SURMOUNT trials show about Mounjaro (tirzepatide) results over weeks, months and years, why results vary and what happens if treatment stops.
12 min read
Results and evidence Realistic Weight Loss Expectations on GLP-1 Treatment
How much weight people lose on Mounjaro, Wegovy and GLP-1 tablets in trials, how results vary, the typical timeline and what affects your own outcome.
12 min read
Results and evidence Wegovy and Heart Health: What the SELECT Trial Found
What the SELECT trial found about semaglutide and heart attacks, strokes and cardiovascular death, who it applies to, and how NICE TA1152 uses it.
13 min read
Results and evidence Wegovy Results: What the STEP Trials Show
What the STEP trials show about Wegovy results: average weight loss over time, how many reach 5%, 10% and 15%, the 7.2mg dose and stopping.
11 min read
Maintenance
Maintenance Mounjaro Maintenance: Staying On, Stepping Down and Stopping
What happens after the weight-loss phase on Mounjaro: maintenance doses, stepping down, stopping, weight regain evidence and how to plan with a prescriber.
12 min read
Maintenance Wegovy Maintenance: What Happens Long Term and When You Stop
What the STEP 4, STEP 5 and SELECT trials show about staying on Wegovy long term, what happens to weight when semaglutide stops, and how to plan.
13 min read
Switching treatment
Switching treatment Switching from an Injection to a GLP-1 Tablet
What to know before moving from a weekly GLP-1 injection to a daily tablet such as Wegovy tablets or Foundayo: evidence, practicalities and prescribing.
12 min read
Switching treatment Switching from Mounjaro to Wegovy
Why some people move from Mounjaro (tirzepatide) to Wegovy (semaglutide), what the evidence says about results, and how prescribers manage the change.
15 min read
Switching treatment Switching from Wegovy to Mounjaro
Switching from Wegovy to Mounjaro in the UK: why people switch, the evidence, timing, starting dose, side effects and questions for your prescriber.
13 min read
Switching treatment Switching Providers Mid-Treatment: What You Need to Know
How to change online weight-loss provider safely during Mounjaro or Wegovy treatment: evidence needed, avoiding gaps, dose continuity and regulation.
12 min read
Exercise
Exercise Exercise on GLP-1 Medication: A Practical Guide
How to exercise safely on Mounjaro, Wegovy or other GLP-1s: what to do, how much, managing low energy and side effects, and why strength work matters.
12 min read
Exercise Preserving Muscle Mass on GLP-1 Treatment
Does Mounjaro or Wegovy cause muscle loss? What trial body-composition data show, who is most at risk, and the evidence-based steps that help protect muscle.
12 min read
Exercise Strength Training for Beginners on Weight Loss Medication
A step-by-step beginner's guide to strength training on Mounjaro, Wegovy or other GLP-1 medicines, with home and gym routines, progressions and safety tips.
13 min read
Diet and nutrition
Diet and nutrition A Sample Week of Eating on GLP-1 Treatment
A flexible, example seven-day meal plan for people on Mounjaro, Wegovy or other GLP-1 medicines, built around protein, fibre, fluids and small portions.
13 min read
Diet and nutrition Foods That Can Worsen GLP-1 Side Effects
Which foods and drinks commonly worsen nausea, reflux, bloating and other side effects on Mounjaro, Wegovy and other GLP-1 medicines, and what to try instead.
13 min read
Diet and nutrition Hydration on GLP-1 Medication
Why dehydration can happen on Mounjaro, Wegovy and other GLP-1 medicines, the warning signs to know, and practical ways to drink enough when you feel full.
12 min read
Diet and nutrition Protein Intake on Weight Loss Injections
How much protein you may need on Mounjaro, Wegovy or other GLP-1 treatment, why it matters for muscle, and practical ways to eat enough with a small appetite.
13 min read
Diet and nutrition Vitamins and Supplements on GLP-1 Treatment
Do you need vitamins on Mounjaro or Wegovy? The evidence on micronutrients, vitamin D, iron, B12 and fibre supplements and products to be wary of.
12 min read
Diet and nutrition What to Eat on GLP-1 Medication
Practical, evidence-based eating guidance for Mounjaro, Wegovy and GLP-1 tablets: protein, fibre, fluids, portions, side effects and nutrients to watch.
12 min read
Plateaus
Plateaus Weight Loss Plateaus on GLP-1 Medication
Why weight loss slows or stalls on Mounjaro or Wegovy, what trials show about plateaus, and the practical and clinical options to discuss with a prescriber
12 min read
Plateaus What If GLP-1 Treatment Doesn't Work for You?
Why some people lose little weight on Mounjaro or Wegovy, how response is judged, NICE's 5% review point and the options a prescriber may discuss.
12 min read
Long-term treatment
Long-term treatment Long-Term GLP-1 Use: What the Evidence Shows
What multi-year trials such as SELECT, STEP 5 and SURMOUNT-1 show about long-term Mounjaro and Wegovy use: weight, heart health, safety and monitoring.
12 min read
Long-term treatment Obesity as a Chronic Disease: Why Medication Has a Role
Why obesity is now treated as a long-term condition, the biology behind weight regain, and where medicines fit in UK obesity treatment.
13 min read
Long-term treatment Weight Regain After Stopping GLP-1 Medication
What trials such as STEP 1 extension, STEP 4 and SURMOUNT-4 show about weight regain after stopping Mounjaro or Wegovy, and how to plan with a prescriber.
12 min read
Choosing a provider
Choosing a provider GPhC, CQC and MHRA: Who Regulates Online Weight Loss Services?
How UK online pharmacies and online doctors offering weight loss treatment are regulated by the GPhC, CQC, MHRA, GMC, NMC and ASA, and how to check them.
12 min read
Choosing a provider How to Choose an Online Pharmacy for Weight Loss Treatment
A practical checklist for choosing a UK online pharmacy for weight loss treatment: registration checks, clinical safeguards, aftercare and clear costs.
12 min read
Choosing a provider Online Doctor Weight Loss Services in the UK Explained
How online doctor weight loss services work in the UK: who prescribes, how they are regulated, what the process involves, and their pros and cons.
13 min read
Choosing a provider Weight Loss Clinics vs Online Providers
Weight loss clinics vs online providers in the UK: how face-to-face and remote GLP-1 services compare on assessment, regulation, support and cost.
13 min read
Safety
Safety Fake and Unlicensed Weight Loss Jabs: How to Spot Them
How to spot fake Mounjaro, counterfeit Wegovy and unlicensed weight loss jabs in the UK, the health risks involved, and what to do if you have used one.
13 min read
Safety Getting Weight Loss Injections Online Safely
How to get weight loss injections such as Mounjaro or Wegovy online safely in the UK: legal routes, registration checks, warning signs and safe home use.
12 min read
Safety GLP-1 Medication and Mental Health
What regulators have concluded about Mounjaro, Wegovy and mood, depression and suicidal thoughts, plus eating disorders, body image and when to get help.
12 min read
Safety GLP-1 Medication Before Surgery and Anaesthesia
What UK guidance says about Mounjaro, Wegovy and other GLP-1 medicines before surgery, sedation and endoscopy, and why telling your team matters.
13 min read
Safety GLP-1 Medication Interactions
How Mounjaro, Wegovy and GLP-1 tablets interact with other medicines, including the contraceptive pill, diabetes treatments, warfarin and levothyroxine.
13 min read
Safety Mounjaro and Alcohol: What You Need to Know
Can you drink alcohol on Mounjaro? What the UK licence says, how alcohol affects side effects, pancreatitis and blood sugar, and how to drink more safely.
15 min read
Specific groups
Specific groups GLP-1 Medication and PCOS
What the evidence says about Mounjaro, Wegovy and other GLP-1 medicines for weight management in PCOS (now PMOS), plus fertility, contraception and safety.
12 min read
Specific groups GLP-1 Medication and the Menopause
How the menopause affects weight, what the evidence says about Mounjaro, Wegovy and HRT, and the contraception, bone and muscle issues to consider.
13 min read
Specific groups GLP-1 Medication and Type 2 Diabetes
How GLP-1 medicines such as Mounjaro, Ozempic and Wegovy are used in type 2 diabetes, what NICE recommends, expected weight loss, low blood sugar and eye risks.
12 min read
Specific groups GLP-1 Medication for People Over 65
How weight loss injections and tablets apply to people over 65: licensing, benefits, muscle, kidneys, other medicines and what prescribers check.
13 min read
Specific groups GLP-1 Medication, Pregnancy and Fertility
What UK guidance says about Mounjaro, Wegovy and pregnancy: wash-out periods, fertility changes, unplanned pregnancy, breastfeeding and planning ahead safely.
12 min read
Specific groups Mounjaro, GLP-1s and Contraception
How Mounjaro can affect the contraceptive pill, what the MHRA advises for all GLP-1 medicines, which methods to consider, and wash-out periods before pregnancy.
12 min read
FAQs
FAQs GLP-1 Medications: 50 Common Questions Answered
Fifty common questions about GLP-1 medicines in the UK, from how they work and who can use them to side effects, NHS access, stopping and safety.
13 min read
FAQs GLP-1 Myths and Facts
Common myths about Mounjaro, Wegovy and other GLP-1 medicines checked against the evidence: weight regain, muscle loss, safety, supplements and more.
13 min read