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Wegovy tablets (oral semaglutide) and nausea: causes, tips and when to get help

Nausea on Wegovy tablets (oral semaglutide): why it happens, self-care measures and the warning signs that need medical help.

About nausea on Wegovy tablets (oral semaglutide)

Feeling sick is one of the most commonly reported effects of GLP-1 medicines. These medicines slow how quickly the stomach empties, which can make you feel full or queasy, particularly when starting treatment or after a dose increase.

Nausea is listed among the commonly reported side effects of Wegovy tablets (oral semaglutide) in our reference data.

Things that may help

  • Eat smaller meals and stop when you start to feel full
  • Eat slowly and avoid lying down straight after eating
  • Limit greasy, fried or very rich foods, which some people find make nausea worse
  • Sip water or other non-fizzy fluids regularly through the day

A pharmacist can advise on suitable over-the-counter options.

Speak to your prescriber if

  • nausea is stopping you eating or drinking normally
  • it has not settled after the first few weeks on a dose
  • you are thinking about increasing your dose while still feeling unwell

Report suspected side effects through the MHRA Yellow Card scheme. Reports help the MHRA monitor the safety of medicines.

Frequently asked questions

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