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Wegovy tablets (oral semaglutide) and constipation: causes, tips and when to get help

Constipation on Wegovy tablets (oral semaglutide): why it happens, self-care measures and the warning signs that need medical help.

About constipation on Wegovy tablets (oral semaglutide)

Slower movement of food through the gut and eating less can both make constipation more likely during GLP-1 treatment.

Constipation is listed among the commonly reported side effects of Wegovy tablets (oral semaglutide) in our reference data.

Things that may help

  • Drink plenty of fluids through the day
  • Include fibre from vegetables, fruit, pulses and wholegrains where you can
  • Stay as physically active as you are able
  • Ask a pharmacist before using a laxative

A pharmacist can advise on suitable over-the-counter options.

Speak to your prescriber if

  • you have not opened your bowels for several days despite self-care
  • constipation is painful or keeps coming back

Report suspected side effects through the MHRA Yellow Card scheme. Reports help the MHRA monitor the safety of medicines.

Frequently asked questions

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