Skip to main content
JabsAndTabs

Oral GLP-1 tablets · orforglipron

Foundayo (orforglipron): UK guide

A once-daily small-molecule GLP-1 tablet authorised in the UK for weight management and type 2 diabetes. Unlike oral semaglutide, it is not a peptide and can be taken at any time of day without food or water restrictions.

Foundayo at a glance

Licensed in the UK for weight managementPrescription-only medicine
Active ingredient
orforglipron
Drug class
Non-peptide (small-molecule) GLP-1 receptor agonist
Manufacturer
Eli Lilly
How it is taken
Tablet, once a day
Dose range
0.8mg to 17.2mg
How to take it
Take once a day at any time of day, with or without food. There are no food or water restrictions.
MHRA authorisation
MHRA authorised for weight management and type 2 diabetes, 10 August 2026
NICE guidance
Not yet verified

Regulatory source: gov.uk

Licensed in the UK for weight management. MHRA authorised for weight management and type 2 diabetes, 10 August 2026.

The main clinical evidence for Foundayo in weight management comes from the ATTAIN trial programme. Read what the trials show for context on realistic expectations.

Foundayo doses

Treatment starts low and steps up gradually to help your body adjust.
Doses listed in the UK product information for Foundayo. Your prescriber decides your dose; not everyone increases to the highest dose.
DoseRoleEarliest start (if increased at every step)
Foundayo 0.8mgStarting doseWeek 1
Foundayo 2.5mgStep-up doseWeek 5
Foundayo 5.5mgStep-up doseWeek 9
Foundayo 9mgMaintenance doseWeek 13
Foundayo 14.5mgMaintenance doseWeek 17
Foundayo 17.2mgMaximum doseWeek 21
  1. Step 10.8mgfrom week 1
  2. Step 22.5mgfrom week 5
  3. Step 35.5mgfrom week 9
  4. Step 49mgfrom week 13
  5. Step 514.5mgfrom week 17
  6. Step 617.2mgfrom week 21

The UK product information says to stay on each dose for at least 4 weeks before increasing. Weeks shown are the earliest possible; many people stay on a dose for longer, and some stay on a lower dose.

Foundayo side effects

Select a side effect for self-care tips and guidance on when to seek help.

When to get urgent help

Stop taking the medicine and get urgent medical help (NHS 111, A&E or 999) if you have severe, persistent stomach pain that may spread to your back, signs of a serious allergic reaction, or yellowing of your skin or eyes. Report suspected side effects to the MHRA Yellow Card scheme.

Everything about Foundayo

How Foundayo compares

UK providers listing Foundayo

Listed alphabetically. Provider details are being verified; we never rank by commission.

We have not yet verified which providers offer Foundayo.

Foundayo: frequently asked questions