Question 1

What is Foundayo?

Accepted Answer

Foundayo is the brand name for orforglipron. It is a non-peptide (small-molecule) GLP-1 receptor agonist made by Eli Lilly. A once-daily small-molecule GLP-1 tablet authorised in the UK for weight management and type 2 diabetes. Unlike oral semaglutide, it is not a peptide and can be taken at any time of day without food or water restrictions. It is a prescription-only medicine, so a registered prescriber must assess whether it is suitable for you.

Question 2

How often is Foundayo taken?

Accepted Answer

Foundayo is taken once a day as a tablet. Take once a day at any time of day, with or without food. There are no food or water restrictions. Always follow your prescriber's instructions and the Patient Information Leaflet that comes with your medicine.

Question 3

What is the starting dose of Foundayo?

Accepted Answer

Treatment usually starts at 0.8mg and the dose is increased gradually, with at least 4 weeks on each dose. Starting low helps the body adjust and can reduce side effects such as nausea. Your prescriber decides if and when to increase your dose.

Question 4

Is Foundayo licensed in the UK for weight loss?

Accepted Answer

Licensed in the UK for weight management. MHRA authorised for weight management and type 2 diabetes, 10 August 2026. Licensing can change, so check the MHRA and the SmPC for the latest position.

Question 5

What are the common side effects of Foundayo?

Accepted Answer

Commonly reported side effects include nausea, diarrhoea, constipation, vomiting and indigestion and reflux. These are often most noticeable when starting treatment or after a dose increase. Seek urgent help if you have severe, persistent stomach pain that may spread to your back. The Patient Information Leaflet lists all known side effects.

Question 6

Can I get Foundayo on the NHS?

Accepted Answer

At the time of writing, NICE has not published guidance on Foundayo for weight management, so it is not generally available on the NHS for this use. This may change once NICE completes its appraisal. Your GP can tell you what NHS weight management support is available locally.

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