Foundayo results: what the evidence shows
What clinical trials of Foundayo (orforglipron) show about weight loss, and how to set realistic expectations.
What the evidence shows about Foundayo
The weight-management licence for Foundayo is based mainly on the ATTAIN programme of randomised controlled trials, which compared orforglipron with placebo in people also following diet and activity advice. Our in-depth guides summarise each trial and link to the published papers.
Trial averages do not predict what will happen to any individual. Results vary with dose, how long treatment continues, other health conditions and changes to diet and activity. Some people lose much less weight than average.