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Foundayo 2.5mg: step-up dose explained

What the 2.5mg dose of Foundayo (orforglipron) is for, where it sits in the step-up schedule and what to discuss with your prescriber.

Where 2.5mg fits

  1. Step 10.8mgfrom week 1
  2. Step 22.5mgfrom week 5
  3. Step 35.5mgfrom week 9
  4. Step 49mgfrom week 13
  5. Step 514.5mgfrom week 17
  6. Step 617.2mgfrom week 21

The UK product information says to stay on each dose for at least 4 weeks before increasing. Weeks shown are the earliest possible; many people stay on a dose for longer, and some stay on a lower dose.

2.5mg is a step-up dose. People usually move through it on the way to a maintenance dose; the earliest it would normally start is week 5. Some people stay on a step-up dose for longer if side effects need time to settle.

Always use the dose your prescriber has prescribed and follow the Patient Information Leaflet. Do not change your dose yourself, and never use a pen or tablet strength that was not prescribed for you.

All Foundayo doses

Doses listed in the UK product information for Foundayo. Your prescriber decides your dose; not everyone increases to the highest dose.
DoseRoleEarliest start (if increased at every step)
Foundayo 0.8mgStarting doseWeek 1
Foundayo 2.5mgStep-up doseWeek 5
Foundayo 5.5mgStep-up doseWeek 9
Foundayo 9mgMaintenance doseWeek 13
Foundayo 14.5mgMaintenance doseWeek 17
Foundayo 17.2mgMaximum doseWeek 21

Frequently asked questions

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