Wegovy 0.25mg: starting dose explained
What the 0.25mg dose of Wegovy (semaglutide) is for, where it sits in the step-up schedule and what to discuss with your prescriber.
Where 0.25mg fits
- Step 10.25mgfrom week 1
- Step 20.5mgfrom week 5
- Step 31mgfrom week 9
- Step 41.7mgfrom week 13
- Step 52.4mgfrom week 17
- Step 67.2mgfrom week 21
The UK product information says to stay on each dose for at least 4 weeks before increasing. Weeks shown are the earliest possible; many people stay on a dose for longer, and some stay on a lower dose.
0.25mg is the starting dose of Wegovy. It is used to help your body get used to the medicine and is not usually intended as a long-term treatment dose. The product information says to stay on it for at least 4 weeks before increasing.
Always use the dose your prescriber has prescribed and follow the Patient Information Leaflet. Do not change your dose yourself, and never use a pen or tablet strength that was not prescribed for you.
All Wegovy doses
| Dose | Role | Earliest start (if increased at every step) |
|---|---|---|
| Wegovy 0.25mg | Starting dose | Week 1 |
| Wegovy 0.5mg | Step-up dose | Week 5 |
| Wegovy 1mg | Step-up dose | Week 9 |
| Wegovy 1.7mg | Step-up dose | Week 13 |
| Wegovy 2.4mg | Maintenance dose | Week 17 |
| Wegovy 7.2mg | Maximum doseAuthorised by the MHRA in January 2026 for adults with obesity (BMI of 30 or more) only. Not covered by NICE TA875. | Week 21 |