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Wegovy tablets (oral semaglutide) dosage: doses and step-up schedule

Wegovy tablets (oral semaglutide) doses and step-up schedule from the UK product information, with guidance on dose increases.

Wegovy tablets (oral semaglutide) dosing schedule

Wegovy tablets (oral semaglutide) is taken once a day. The dose is increased gradually to reduce side effects; your prescriber decides whether and when to increase it, and some people stay on a lower dose if it works well for them or if side effects are troublesome.

Doses listed in the UK product information for Wegovy tablets (oral semaglutide). Your prescriber decides your dose; not everyone increases to the highest dose.
DoseRoleEarliest start (if increased at every step)
Wegovy tablets (oral semaglutide) 1.5mgStarting doseWeek 1
Wegovy tablets (oral semaglutide) 4mgStep-up doseWeek 5
Wegovy tablets (oral semaglutide) 9mgStep-up doseWeek 9
Wegovy tablets (oral semaglutide) 25mgMaintenance doseWeek 13
  1. Step 11.5mgfrom week 1
  2. Step 24mgfrom week 5
  3. Step 39mgfrom week 9
  4. Step 425mgfrom week 13

The UK product information says to stay on each dose for at least 4 weeks before increasing. Weeks shown are the earliest possible; many people stay on a dose for longer, and some stay on a lower dose.

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