Mounjaro and indigestion and reflux: causes, tips and when to get help
Indigestion and reflux on Mounjaro (tirzepatide): why it happens, self-care measures and the warning signs that need medical help.
Get urgent medical help if:
- you have chest pain, especially if it spreads to your arm, jaw or back, or comes with breathlessness (call 999)
- you vomit blood or have black, tarry stools
Call 999 or go to A&E in an emergency. For urgent advice, call NHS 111.
About indigestion and reflux on Mounjaro
Indigestion, heartburn and acid reflux are reported with GLP-1 medicines, which keep food in the stomach for longer.
Indigestion and reflux is listed among the commonly reported side effects of Mounjaro in our reference data.
Things that may help
- Eat smaller meals and avoid eating late in the evening
- Keep your head and shoulders raised in bed if reflux is worse at night
- Notice and limit foods that trigger symptoms for you
- Ask a pharmacist whether an antacid is suitable alongside your other medicines
A pharmacist can advise on suitable over-the-counter options.
Speak to your prescriber if
- symptoms persist despite self-care
- you have difficulty or pain when swallowing
Report suspected side effects through the MHRA Yellow Card scheme. Reports help the MHRA monitor the safety of medicines.
Frequently asked questions
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