How Liraglutide (Saxenda / generic) works
How Liraglutide (Saxenda / generic) works in the body, explained in plain English.
How Liraglutide (Saxenda / generic) works
Liraglutide mimics GLP-1 (glucagon-like peptide-1), a hormone released by the gut after eating. Activating the GLP-1 receptor helps reduce appetite, makes you feel full sooner, slows how quickly the stomach empties and helps regulate blood sugar.
It is taken once a day as an injection under the skin of the stomach, thigh or upper arm. These effects are why digestive side effects such as nausea are common, particularly after starting or increasing the dose.
Licensed in the UK for weight managementPrescription-only medicine
- Active ingredient
- liraglutide
- Drug class
- GLP-1 receptor agonist
- Manufacturer
- Novo Nordisk (Saxenda); generic liraglutide from other manufacturers
- How it is taken
- Injection, once a day
- Device
- Pre-filled pen
- Dose range
- 0.6mg to 3mg
- MHRA authorisation
- Not yet verified
- NICE guidance
- NICE TA664 (December 2020)
Branded Saxenda has reportedly been discontinued in the UK. Generic liraglutide is available. Check current availability before relying on the brand name.
Frequently asked questions
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